May 25, 2011

« To elucidate the sequence-structure correspondence, molecular biologists analyze, compare, and classify protein structures, in a manner perhaps more reminiscent of the activities of art historians than that of physical scientists. »

« There is an analogy between the analysis of protein structures at different levels, and the analysis of text. The amino acids correspond to letters, the secondary structures to words, the supersecondary structures to phrases (or even to cliches) the elements of tertiary structure to sentences — this is the level at which individuality makes its appearance — domains to paragraphs, the structure of a full polypeptide chain as a chapter, and the quaternary structure to the assembly of chapters into a complete book. »

~ Lesk

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